Nonalcoholic fatty liver disease, or NAFLD (also referred to as metabolic dysfunction-associated steatotic liver disease, or MASLD), is a condition in which excess fat builds up in your liver. MASLD may not cause symptoms. NAFLD is usually but not always related to being overweight. Non-alcoholic fatty liver disease (NAFLD) is caused by a buildup of fat in the liver and is the most common form of liver disease in the United States. Introduction Non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of end-stage liver disease, hepatocellular carcinoma, and liver transplantation. MASLD is when fat builds up in your liver because of extra body weight, high blood sugar, high cholesterol, or high blood pressure. These patients Jan 6, 2026 · In patients with NAFLD who require fibrosis staging, AASLD recommends the use of simple, less costly, and readily available blood-based NILDA tests such as FIB-4 or NAFLD fibrosis score over complex proprietary tests for the detection of advanced fibrosis (F3-4; strong recommendation, moderate quality of evidence). Non-Alcoholic Fatty Liver Disease (NAFLD): This is the most common form and occurs in individuals who drink little to no alcohol. For many people, NAFLD causes no symptoms or problems. It affects patients who drink little to no alcohol.

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